Table 3.

Survival times of patients with or without histologically confirmed extramedullary manifestations

Survival times	Hist. EM AML	Non-EM AML	Hazard ratio	Cox regression p-value
Event-free survival	3.6 [1.2–8.4]	8.4 [7.7–9.6]	1.43 [1.01–2.04]	0.046
Relapse-free survival	11.6 [3.9–34.6]	19.3 [16.3–23.7]	1.35 [0.84–2.15]	0.213
Overall survival	8.7 [5.1–20.3]	26.2 [22.4–32.6]	1.84 [1.29–2.64]	< 0.001

In comparison to Table 2, patients with only clinical diagnosis of extramedullary manifestations (EM) were excluded and only data for patients with histologically confirmed EM are shown (n = 38). Survival times in months. Cox-proportional hazard models were used to obtain univariable hazard ratios. Brackets show 95%-confidence intervals. Statistically significant p-values are marked in bold