Table 2.
Gene modules identified by MEGENA
| ID | Module size | Module parent | Module hub | Module scale | Module p value |
|---|---|---|---|---|---|
| c1_2 | 95 | c1_1 | () | S3 | < 1e−5 |
| c1_3 | 29 | c1_1 | UGGT1 (13) | NA | < 1e−5 |
| c1_4 | 90 | c1_1 | MPEG1 (21), IQGAP1 (19) | S3 | < 1e−5 |
| c1_5 | 30 | c1_2 | LUZP6*(13), ANO6 (12) | S3 | < 1e−5 |
| c1_6 | 35 | c1_2 | PTGS1 (15) | S3 | < 1e−5 |
| c1_8 | 12 | c1_2 | () | S3 | < 1e−5 |
| c1_10 | 10 | c1_3 | () | NA | < 1e−5 |
| c1_12 | 64 | c1_4 | MPEG1 (21), IQGAP1 (19) | S2 | < 1e−5 |
| c1_13 | 26 | c1_4 | () | S2 | 0.04 |
| c1_16 | 12 | c1_5 | ANO6(9) | S2 | < 1e−5 |
| c1_18 | 18 | c1_6 | PTGS1 (11), CLU (9) | NA | < 1e−5 |
| c1_23 | 52 | c1_12 | MPEG1 (21), IQGAP1 (17) | NA | < 1e−5 |
| c1_24 | 12 | c1_12 | () | S1 | < 1e−5 |
| c1_25 | 12 | c1_13 | PLCB2*(9) | S1 | < 1e−5 |
| c1_26 | 14 | c1_13 | () | S1 | < 1e−5 |
| c1_29 | 25 | c1_23 | MPEG1 (18) | NA | < 1e−5 |
| c1_34 | 21 | c1_29 | MPEG1 (18) | S1 | < 1e−5 |
Module size means the number of genes in each module, module parent means the beginning from connected components of the initial networks, module hub means the hub gene in this module, module scale demonstrates that three scales groups (S1, S2 and S3) were identified that had similar interaction patterns and shared highly connected hubs across different scales. The numbers inside the parenthesis in column 'module hub' mean the number of genes directed connected to the hub gene