Table 4.
Differentially expressed metabolites between two groups
Metabolites | Estimate | SE | P value | VIP value |
---|---|---|---|---|
Glucosamine/Mannosamine | 0.93 | 0.33 | 0.00 | 1.07 |
Ursodeoxycholic Acid (UDCA) | 0.61 | 0.21 | 0.00 | 1.82 |
3-(2-hydroxyphenyl) propanoate | 0.58 | 0.22 | 0.01 | 1.67 |
Plasmenyl-LysoPE (P-18:1) | − 0.63 | 0.25 | 0.01 | 1.56 |
N-methyl-D-aspartic acid* | − 0.55 | 0.22 | 0.01 | 1.43 |
Sphingosine (d18:1) | 0.53 | 0.21 | 0.01 | 2.12 |
2-deoxy-D-galactose (fructose/glucose) | − 0.65 | 0.26 | 0.01 | 1.35 |
Phenylalanyl-Threonine/Threoninyl-Phenylalanine | 0.52 | 0.22 | 0.02 | 1.37 |
Indole-3-acetate* | − 0.51 | 0.22 | 0.02 | 1.07 |
Isobutyrylcarnitine | − 0.51 | 0.24 | 0.03 | 1.07 |
N-Acetylneuraminate | 0.55 | 0.26 | 0.04 | 1.35 |
Aspartate | − 0.54 | 0.26 | 0.04 | 1.17 |
*Denotes the novel metabolites discovered in the current study