Table 1.
Healthy term (n = 13) | Obese/diabetic (n = 13) | Healthy preterm (n = 10) |
P values |
|||
---|---|---|---|---|---|---|
Term vs. O/D | Term vs. preterm | O/D vs. preterm | ||||
| ||||||
Gestational age (wk/days) | 38 2/7 ± 1 2/7 | 38 1/7 ± 1 1/7 | 31 2/7 ± 1 6/7 | 0.578 | <0.001 | <0.001 |
37 5/7–39 0/7 | 37 3/7–38 5/7 | 30 1/7–32 2/7 | ||||
Birth weight (gm) | 3236 ± 456 | 3837 ± 123 | 1695 ± 473 | 0.494 | <0.001 | <0.001 |
2988–3484 | 3771–3903 | 1402–1988 | ||||
Mother’s BMI | 29.6 ± 7.0 | 42.1 ± 13.2 | 26.6 ± 4.2 | 0.010 | 0.167 | <0.001 |
25.5–33.7 | 35.0–49.2 | 23.5–29.7 | ||||
Serum iron (μg/dL) | 219 ± 201 | 124 ± 63 | 101 ± 67 | 0.049 | 0.039 | 0.617 |
110–329 | 87–161 | 63–156 | ||||
TIBC (μg/dL) | 216 ± 39 | 230 ± 68 | 191 ± 22 | 0.531 | 0.158 | 0.155 |
195–237 | 190–269 | 168–214 | ||||
Serum ferritin (ng/mL) | 136 ± 49 | 152 ± 181 | 70 ± 69 | 0.368 | 0.030 | 0.246 |
110–162 | 11–258 | 22–118 | ||||
Hgb (g/dL) | 15.6 ± 1.5 | 15.3 ± 1.2 | 17.7 ± 1.7 | 0.590 | 0.012 | 0.002 |
14.6–17.4 | 14.6–16.0 | 16.7–19.7 | ||||
HCT (%) | 47.0 ± 5.1 | 46.1 ± 3.5 | 50.3 ± 5.1 | 0.637 | 0.177 | 0.043 |
44.0–50.7 | 44.1–48.1 | 47.2–53.4 | ||||
MCV (fL) | 105.9 ± 2.9 | 107.8 ± 4.8 | 111.9 ± 8.3 | 0.295 | 0.045 | 0.180 |
104.1–107.7 | 105.0–110.6 | 106.8–117.0 | ||||
MCH (pg) | 34.9 ± 1.5 | 35.7 ± 2.2 | 39.1 ± 3.9 | 0.335 | 0.003 | 0.023 |
34.0–35.8 | 34.4–37.0 | 36.7–41.5 | ||||
Retics (%) | 4.3 ± 0.8 | 4.3 ± 0.9 | 6.8 ± 1.3 | 0.720 | <0.001 | <0.001 |
3.8–4.8 | 3.9–10.3 | 5.6–8.0 | ||||
RET-He (pg) | 34.5 ± 2.2 | 33.2 ± 3.8 | 36.6 ± 9.6 | 0.406 | 0.016 | 0.038 |
33.0–35.8 | 31.0–35.4 | 35.9–38.0 | ||||
Erythropoietin (mU/mL) | 4.5 ± 6.0 | 18.5 ± 44.7 | 4.7 ± 6.1 | 0.298 | 0.826 | 0.749 |
1.3–7.7 | 0.0–53.0 | 1.0–7.4 | ||||
Erythroferrone (ng/mL) | 1.6 ± 1.3 | 2.8 ± 4.1 | 1.0 ± 0.8 | 0.952 | 0.337 | 0.646 |
0.9–2.3 | 0.4–5.2 | 0.5–1.5 | ||||
Hepcidin (ng/mL) | 70.8 ± 37.0 | 34.2 ± 21.3 | 30.5 ± 22.8 | 0.043 | 0.004 | 0.069 |
52.1–89.5 | 19.4–49.0 | 15.6–45.4 |
Wk, week; gm, gram; TIBC, total iron binding capacity; Hgb, hemoglobin; HCT, hematocrit; MCV mean corpuscular volume; MCH, mean corpuscular hemoglobin; Retics, reticulocytes; RET—He, reticulocyte hemoglobin content; O/D, obese and diabetic.