Table 2.
Main effect of group in the global network metrics
| HC | svPPA | nfvPPA | HC vs svPPA p-value (effect size) |
HC vs nfvPPA p-value (effect size) |
svPPA vs nfvPPA p-value (effect size) |
|
|---|---|---|---|---|---|---|
| σ | 0.52 ± 0.07 | 0.44 ± 0.05 | 0.51 ± 0.07 | < 0.001 (1.34) | 0.42 (0.16) | < 0.001 (−1.16) |
| λ | 0.42 ± 0.01 | 0.44 ± 0.02 | 0.43 ± 0.02 | < 0.001 (−1.78) | < 0.001 (−0.66) | 0.001 (0.83) |
| γ | 0.75 ± 0.09 | 0.67 ± 0.07 | 0.75 ± 0.09 | < 0.001 (0.98) | 0.95 (−0.01) | < 0.001 (−0.98) |
All graph measure values are expressed as the area under the curve (AUC) across density range
σ, small-worldness index; λ, normalized characteristic path length; γ, normalized clustering coefficient; Eglob: global efficiency; HC: healthy controls; svPPA: semantic variant of primary progressive aphasia; nfvPPA: progressive nonfluent variant of primary progressive aphasia