Fig. 5.

POSTN boosts in vivo the lymphangiogenic response initiated by VEGF-C. Inguinal LNs were injected with recombinant POSTN, VEGF-C or a combination of both for 3 days. a Morphometric analysis of LYVE1 lymphatic vessels (in green) in inguinal LNs 3 days after injection. Bars = 250 µm. b Scatter graph uses scatter plots to represent LYVE1 density assessed by a computer assisted method. Results are expressed as mean ± SD (n ≥ 6), and statistical analyses were performed using a Wilcoxon–Mann–Whitney test (*p < 0.05, **p < 0.01)