Table 1.

Summary of seven dynamic susceptibility-contrast MRI protocols run across six scanners at four centers in this multicenter study

Center	1		2	3	4
Scanner type	Siemens Avanto	Philips Achieva	Siemens Verio	Philips Achieva	Philips Achieva	Philips Achieva	Philips Achieva
Field strength	1.5 T	3 T	3 T	3 T	1.5 T	3 T	3 T
Head coil	12-element head	32-channel	32-channel	SENSE head-8	SENSE-NV-16	SENSE head-8	SENSE head-8
Sequence	GE-EPI	GE-EPI	GE-EPI	GE-EPI	sPRESTO	sPRESTO	GE-EPI
TR (ms)	1,490–1,643	1,830–1,865	1,570	1,666–2,343	16.7–17.2	15.5–16.0	582–1,866
TE (ms)	40	40	29	40	24.7–25.2	23.5–24.0	18.4–40.0
Flip angle (o)	20	20	45	75	7	7	20–40
Slice thickness (mm)	5.0	3.5	3.5	4.0	3.5	3.5	3.5–7.0
No. slices	19–21	30	16	25–35	30–36	30–34	30
No. dynamics	60	60	60	40	60	60	40–60
Field-of-view (mm)	230×230	240×240	220×220	224×224	220×220	230×230	240×240
Matrix	96×96	96×96	64×64	128×128	64–80×64–80	128×128	96×96
SENSE?	Y	Y	N	Y	Y	Y	Y
Temporal resolution (s)	1.5–1.6	1.8–1.9	1.6	1.7–2.3	1.3–1.6	1.2–1.4	0.6–1.9
Total scan time (s)	90–99	110–112	94	67–94	77–94	71–83	70–118
Pre-bolus	Y	Y	N	Y	Y (n=12), N (n=15), NA (n=9)
Pre-bolus dose	Half	Half	–	1 mL	Range = 0.3–2.0 mL (10% of dose)
Injection rate (mL/s)	3	3	6	3	3	3	3
Contrast agent	Dotarem	Dotarem	Dotarem	Dotarem	Magnevist (n=20), Gadovist (n=10), NA (n=6)
No. patients	8	3	12	26	15	16	5

GE-EPI gradient echo echoplanar imaging, n number, N no, NA not available, No. number, SENSE sensitivity encoding, sPRESTO sensitivity-encoded Philips principles of echo-shifting with a train of observations, T tesla, TE time to echo, TR time to repetition, Y yes