Table 5.
Mean parameters for the low- and high-grade tumor groups, respectively, along with 95% confidence intervals; cut-off values for differentiating between low- and high-grade tumors are shown alongside the specificity, sensitivity, positive and negative predictive values of each parameter when this cut-off is employed
| Whole-tumor median of parameter | Grade | Mean | 95% confidence interval for mean | Cut-off value | Sensitivity (%) | Specificity (%) | Positive predictive value (%) | Negative predictive value (%) |
|---|---|---|---|---|---|---|---|---|
|
Uncorrected rCBV |
Low-grade | −0.14 | −1.91–1.64 | 1.60 | 53.3 | 82.5 | 77.4 | 61.1 |
| High-grade | 2.37 | 1.58–3.15 | ||||||
| Corrected rCBV | Low-grade | 1.68 | 1.24–2.11 | 1.70 | 75.6 | 65.0 | 70.8 | 70.3 |
| High-grade | 2.54 | 2.05–3.03 | ||||||
| K2 | Low-grade | 0.017 | 0.002–0.033 | 0.001 | 60.0 | 75.0 | 73.0 | 62.5 |
| High-grade | 0.002 | −0.003–0.007 |
K2 leakage parameter, rCBV relative cerebral blood volume