Table 4.
Summary of studies using Tachosil for sellar closure during transsphenoidal surgery.
| Closure technique | Approach | Material | N patient exposed | Intraoperative CSF leak | PO CSF leak | LD | Surgery | Remark |
|---|---|---|---|---|---|---|---|---|
| TACHOSIL | EETS (present sudy) | One layer Tachosil + Tissucol | 65 | 12 | 7.7% (5/65) | 2 | 0 |
Cost Virus transmission + easily removed in revision repair + immunologically well tolerated + hemostasis + lower postoperative infection |
| MTS ± endoscope15 | Sandwich technique | 101 | 18 | 1.9% (2/101) | 0 | 0 | ||
| MTS20 | Sandwich technique | 19 | 19 | 5.3% (1/19) | 0 | 0 | ||
| MTS − EETS21 | Surgicel + Tachosil | 29 | 29 | 0% (0/29) | 0 | 0 |
N number, PO postoperative, LD lumbar drainage, EETS endonasal endoscopic transphenoidal surgery, MTS microscopic transsphenoidal surgery.