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. 2022 May 14;13(5):460. doi: 10.1038/s41419-022-04900-y

Fig. 1. Schematic representation of the extrinsic and intrinsic apoptosis pathways, indicating pharmacological agents and their therapeutic targets.

Fig. 1

Proteins mediating similar functions are indicated by shading, while green shaded boxes highlight pharmacological agents. ↑ and ↓ indicates that the target is upregulated or downregulated by the drug, respectively. --| indicates inhibition of the target protein by the specified protein/drug. Created with BioRender.com.