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. 2022 May 14;12:8008. doi: 10.1038/s41598-022-11760-1

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Differential gene analysis and prognosis analysis of esophageal cancer. (A) 1220 DEGs differentially expressed between the EC and adjacent tissues. Red dots represent differentially expressed up-regulated genes, green dots represent differentially expressed down-regulated genes, and black dots represent no significant difference in gene expression. (B) Kaplan–Meier (KM) prognostic analysis of DEGs. 41 genes of 1220 genes in the DEGs were associated with the prognosis of patients with esophageal cancer.