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. Author manuscript; available in PMC: 2022 Nov 15.
Published in final edited form as: Nat Cell Biol. 2022 May 9;24(5):748–756. doi: 10.1038/s41556-022-00897-w

Extended Data Fig. 4. CENP-A nucleosomes are retained through the replacement of canonical nucleosomes with protamines during spermiogenesis.

Extended Data Fig. 4

a, Quantification and b, images showing CENP-A levels are reduced to 42.7 ± 1.5% in spermatids from Cenpa+/− males compared to WT males, similar to the reduction measured in prophase spermatocytes (Fig. 1c). N = 20 (control), 32 (Cenpa+/−) spermatids. Error bars: median ± 95% CI. Scale bars: 5 μm (main panel), 1μm (inset). Source numerical data are available in source data.