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. Author manuscript; available in PMC: 2022 Nov 15.
Published in final edited form as: Nat Cell Biol. 2022 May 9;24(5):748–756. doi: 10.1038/s41556-022-00897-w

Fig. 5: CENP-A chromatin recovers in adult male F2 progeny from Cenpa+/+ WT F1 parents.

Fig. 5:

a, Mating scheme to generate F2 generation from F1 with epigenetically weakened centromeres and wild type genotype. b, Prophase I spermatocytes from control and F2 males. Each of the CENP-A foci represents four centromeres from a pair of homologous chromosomes. Scale bars: 5 μm (main panel), 1μm (inset). c, Quantification of CENP-A foci intensities. N = 276 (control), 328 (F2) centromeres. n.s. P>0.05, Mann-Whitney U test (two tailed). Error bars: median ± 95% CI. Source numerical data are available in source data.