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. 2022 May 14;10(3):e00954. doi: 10.1002/prp2.954

FIGURE 2.

FIGURE 2

Ivermectin inhibits multiple oncogenic signaling in hepatocellular carcinoma cells. Western blot analysis of molecules involved in mTOR/STAT3 signalling (A), EMT (B) and stemness (C) in SNU‐182 cells. (D) Ivermectin decreases mRNA levels of STAT3‐targted genes (MCL‐1, BCL‐XL and C‐MYC) and stem cell marker genes (OCT‐4, SOX‐2 and NANOG) in SNU‐182 cells. Western blot and real‐time PCR were performed after 24 h drug treatment