Table 2.

List of top 64 proteins significantly differing in abundance between AD and control subjects in the EMIF-AD cohort

Accession number	Gene name	BH-corrected p-value	log2-fold change	Number of observations control	Number of observations AD
P63104	YWHAZ	1.4E−24	0.49	122	91
P62258	YWHAE	1.8E−21	0.37	122	91
P09936	UCHL1	4.1E−19	0.37	106	77
Q9H4F8	SMOC1	5.8E−16	0.31	120	90
P61981	YWHAG	7.2E−14	0.31	109	83
P07196	NEFL	7.5E−13	0.58	69	52
P18669	PGAM1	7.5E−13	0.20	109	84
P05413	FABP3	5.6E−12	0.29	112	82
P31150	GDI1	5.6E−12	0.17	123	88
P47972	NPTX2	4.4E−11	−0.35	125	91
P62937	PPIA	1.8E−10	0.20	121	89
P00558	PGK1	3.0E−10	0.15	114	90
O94760	DDAH1	4.9E−08	0.18	124	93
P10636	MAPT	6.9E−07	0.40	56	45
P14174	MIF	9.7E−07	0.19	101	82
P04075	ALDOA	2.2E−06	0.19	124	90
P62942	FKBP1A	2.5E−06	0.21	105	78
Q92686	NRGN	4.3E−06	0.31	99	73
P16949	STMN1	5.8E−06	0.20	118	87
P40925	MDH1	6.0E−06	0.19	125	89
P33908	MAN1A1	6.0E−06	− 0.08	122	91
O95502	NPTXR	7.5E−06	− 0.24	126	91
Q6EMK4	VASN	1.2E−05	0.10	123	91
Q9Y2T3	GDA	1.4E−05	0.24	125	93
P12277	CKB	1.8E−05	0.14	120	90
Q12805	EFEMP1	1.8E−05	0.12	125	91
P36222	CHI3L1	2.2E−05	0.26	124	92
P06744	GPI	2.2E−05	0.21	73	67
P00492	HPRT1	2.4E−05	0.20	119	87
Q92765	FRZB	2.4E−05	0.20	125	92
O15240	VGF	2.7E−05	− 0.26	124	90
P60983	GMFB	3.9E−05	0.11	121	89
Q13421	MSLN	7.3E−05	− 0.23	121	89
O00142	TK2	2.6E−04	0.13	107	81
Q13228	SELENBP1	2.7E−04	− 0.15	124	90
P23297	S100A1	3.0E−04	0.22	48	33
P17677	GAP43	3.0E−04	0.19	126	90
Q92743	HTRA1	3.1E−04	0.09	126	92
P0DP23	CALM1	3.7E−04	0.16	120	89
P06733	ENO1	3.8E−04	0.14	119	89
P31946	YWHAB	3.9E−04	0.17	116	90
Q9HCB6	SPON1	4.2E−04	0.11	125	91
P62328	TMSB4X	4.6E−04	0.15	124	90
P10451	SPP1	6.1E−04	0.16	126	90
Q9Y279	VSIG4	6.3E−04	0.17	123	88
P29120	PCSK1	6.3E−04	− 0.22	121	90
P14618	PKM	7.4E−04	0.15	119	90
P10599	TXN	8.0E−04	0.11	121	89
P05060	CHGB	8.6E−04	− 0.14	125	90
P55286	CDH8	1.5E−03	− 0.11	124	91
Q14697	GANAB	1.6E−03	− 0.09	124	89
P01213	PDYN	1.8E−03	− 0.14	123	91
Q06830	PRDX1	1.9E−03	0.10	120	87
Q5VSG8	MANEAL	2.1E−03	− 0.10	124	90
Q9H2A7	CXCL16	2.7E−03	0.16	85	63
P08637	FCGR3A	2.8E−03	0.16	111	88
P54756	EPHA5	3.2E−03	− 0.13	126	93
O60241	ADGRB2	3.5E−03	− 0.13	121	90
P09104	ENO2	3.6E−03	0.12	125	89
Q92932	PTPRN2	3.8E−03	− 0.13	125	93
P13521	SCG2	4.5E−03	− 0.16	123	91
P01303	NPY	4.6E−03	− 0.24	99	71
P30086	PEBP1	5.3E−03	0.10	123	91
P01210	PENK	6.3E−03	− 0.12	121	90

Data was normalized employing the TAMPOR function