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Cardiovascular benefits of SGLT2 inhibitors
| Agents | MACEs (HR) | CV death (HR) | HF (HR) | Renal outcome (HR) |
|---|---|---|---|---|
| Empagliflozin [56] | 0.86 | 0.62 | 0.65 | 0.5 |
| Canagliflozin [57] | 0.86 | 0.87 | 0.67 | 0.6 |
| Dapagliflozin [58] | 0.93 | 0.98 | 0.73 | 0.76 |
| Ertugliflozin [59] | 0.97 | 0.92 | 0.7 | 0.81 |
| Tofogliflozin [60] | – | – | – | – |
| Luseogliflozin [61] | – | – | – | – |
| Ipragliflozin [61] | – | – | – | – |
– limited data, MACE major adverse cardiac event, HR hazard ratio, CV cardiovascular, HF heart failure
