Table 7.

Targets for lipid control

Parameter		Target	Population	Guideline	References
Lipid	LDL-C	Reduction of ≥ 50% or more from baseline	Adults with diabetes and 10 year atherosclerotic CVD risk of 20% or higher	ADA	[91]
	LDL-C	Reduction of ≥ 50% from baseline	Patients with DM and atherosclerotic CVD	AHA	[39]
	LDL-C	Reduction of ≥ 50% from baseline and < 70 mg/dL	Patients with T2DM > 40 years of age at high CVD risk	ESC	[41]
		LDL-C Reduction of ≥ 50% from baseline and < 55 mg/dL	Patients with T2DM at very high CVD risk
	LDL-C	< 100 mg/dL	Patients with T2DM at moderate CV risk	ESC/EASD	[94]
		< 70 mg/dL	Patients with T2DM at high CV risk
		< 55 mg/dL	Patients with T2DM at very high CV risk

CV cardiovascular, ASCVD atherosclerotic cardiovascular disease, ADA American Diabetes Association, ESC European Society of Cardiology, EASD European Association for the Study of Diabetes, AHA American Heart Association, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, DM diabetes mellitus