Table 3.
The details of glycolysis/gluconeogenesis pathway related genes
| NO. | Gene name | Chromosome | Fold change | P value | FDR | Regulation |
|---|---|---|---|---|---|---|
| 1 | LDHB | 4 | 0.324 | 9.015E-05 | 0.012 | Down |
| 2 | PGM1 | 5 | 0.376 | 0.002 | 0.029 | Down |
| 3 | HK1 | 20 | 0.638 | 0.002 | 0.030 | Down |
| 4 | GPI | 1 | 0.483 | 0.003 | 0.036 | Down |
| 5 | PFKM | 7 | 0.378 | 0.003 | 0.036 | Down |
| 6 | PFKL | 20 | 0.368 | 0.005 | 0.043 | Down |
| 7 | PK | 8 | 0.529 | 0.008 | 0.052 | Down |
| 8 | ACSS2 | 3 | 0.338 | 0.011 | 0.060 | Down |
| 9 | ALDH3A2 | 10 | 0.634 | 0.011 | 0.060 | Down |
| 10 | LDHA | 1 | 0.493 | 0.012 | 0.062 | Down |
| 11 | ALDOC | 10 | 0.249 | 0.012 | 0.064 | Down |
| 12 | PGAM1 | 1 | 0.496 | 0.014 | 0.069 | Down |
| 13 | HK2 | 4 | 0.508 | 0.015 | 0.070 | Down |
| 14 | GAPDH | 4 | 0.546 | 0.016 | 0.072 | Down |
| 15 | TPI1 | 4 | 0.435 | 0.019 | 0.079 | Down |
| 16 | ALDOA | 1 | 0.664 | 0.022 | 0.084 | Down |
| 17 | PGK1 | X | 0.471 | 0.027 | 0.095 | Down |
| 18 | ALDH7A1 | 18 | 0.608 | 0.029 | 0.100 | Down |
| 19 | ENO1 | 5 | 0.657 | 0.031 | 0.102 | Down |
| 20 | GALM | 6 | 0.579 | 0.044 | 0.124 | Down |
FDR the adjusted P value, P value the P value of the F-statistic for gene from young and old MSCs, AcCSS2 acyl-CoA synthetase short-chain family member 2, ALDH3A2 aldehyde dehydrogenase 3 family member A2, ALDH7A1 aldehyde dehydrogenase 7 family member A1, ALDOA aldolase fructose-bisphosphate, ALDOC aldolase fructose-bisphosphate C, ENO1 enolase 1, GALM galactose mutarotase, GAPDH glyceraldehyde-3-phosphate dehydrogenase, PFKL phosphofructokinase liver type, PFKM phosphofructokinase muscle, PGK1 phosphoglycerate kinase 1, PGM1 phosphoglucomutase 1, PK pyruvate kinase, GPI glucose-6-phosphate isomerase, HK1 hexokinase 1, HK2 hexokinase 2, LDHA lactate dehydrogenase A, LDHB lactate dehydrogenase B, PGAM1 phosphoglycerate mutase 1, TPI1 triosephosphate isomerase 1