Table.
Case No | Reference | Patient age/gender | Time duration from COVID-19 to onset of neuroligal symptoms | CNS lesions | CSF findings | Treatment | Clinical outcome |
---|---|---|---|---|---|---|---|
1 | 16 | 47/M | No symptoms of infection | Bilateral optic neuritis | CSF normal cell cout and chemistry, RT-PCR negative for SARS-CoV-2 | IVMP, oral steroid | Recoverd |
2 | 17 | 11/M | 2 weeks | Bilateral optic neuritis | CSF WBC 55 cells/μL, noraml protein OCB absent | IVMP, oral steroid | Recoverd |
3 | 18 | 44/M | 2 weeks | Bilateral optic neuritis | CSF WBC 3 cells/μL, protein 50 mg/dL, OCB absent | IVMP, oral steroid | Recoverd |
4 | 2 | 26/M | 2 days | Bilateral optic neuritis, myelitis | CSF WBC 55 cells/μL, protein 31 mg/dL, OCB present RT-PCR negative for SARS-CoV-2 | IVMP, oral steroid | Recoverd |
5 | 19 | 44/F | 1 weeks | CNS inflammatory vasculopathy | CSF WBC 13 cells/μL, protein 507 mg/L, RT-PCR negative for SARS-CoV-2 | IVMP, oral steroid, PE | Recoverd |
6 | Current case | 24/F | 3 weeks | Unilataral optic neuritis, myelitis, CNS demyelinatining lesions | CSF WBC 16 cells/μL, protein 51 mg/dL, OCB present RT-PCR negative for SARS-CoV-2 | IVMP, oral steroid | Recoverd |
CNS: central nervous system, WBC: white blood count, OCB: oligoclonal band, IVMP: intravenous methylprednisolone, PE: plasma exchange