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. 2022 Feb 8;61(8):1253–1258. doi: 10.2169/internalmedicine.8709-21

Table.

Clinical Characteristics of Reported Cases of MOG Antibody-associagted Disease after SARS-CoV-2 Infection.

Case No Reference Patient age/gender Time duration from COVID-19 to onset of neuroligal symptoms CNS lesions CSF findings Treatment Clinical outcome
1 16 47/M No symptoms of infection Bilateral optic neuritis CSF normal cell cout and chemistry, RT-PCR negative for SARS-CoV-2 IVMP, oral steroid Recoverd
2 17 11/M 2 weeks Bilateral optic neuritis CSF WBC 55 cells/μL, noraml protein OCB absent IVMP, oral steroid Recoverd
3 18 44/M 2 weeks Bilateral optic neuritis CSF WBC 3 cells/μL, protein 50 mg/dL, OCB absent IVMP, oral steroid Recoverd
4 2 26/M 2 days Bilateral optic neuritis, myelitis CSF WBC 55 cells/μL, protein 31 mg/dL, OCB present RT-PCR negative for SARS-CoV-2 IVMP, oral steroid Recoverd
5 19 44/F 1 weeks CNS inflammatory vasculopathy CSF WBC 13 cells/μL, protein 507 mg/L, RT-PCR negative for SARS-CoV-2 IVMP, oral steroid, PE Recoverd
6 Current case 24/F 3 weeks Unilataral optic neuritis, myelitis, CNS demyelinatining lesions CSF WBC 16 cells/μL, protein 51 mg/dL, OCB present RT-PCR negative for SARS-CoV-2 IVMP, oral steroid Recoverd

CNS: central nervous system, WBC: white blood count, OCB: oligoclonal band, IVMP: intravenous methylprednisolone, PE: plasma exchange