. 1999 Feb;65(2):686–693. doi: 10.1128/aem.65.2.686-693.1999

TABLE 2.

Seven conserved helicase motifs found in the EcoP1, StyLTI, and LlaFI Res subunits

R/M subunit	Helicase motifs^a
R/M subunit	I	IA	II	III	IV	V	VI
EcoP1 Res	`IDVSMETGTGKTYTYTk`	`NKFIIIVPT1SIKAGT`	`FIIIDEpH`	`IIRYGATFS`	`TLFFIDdIEG`	`FIFSKWTLREGWDNPNVFQIC`	`STTSKLQEVGRGLR`
StyLTI Res	`IdVKMETGTGKTYVYTr`	`FKFVLVVPTpAIKEGA`	`VVIIDEpH`	`IIrYgATFS`	`tLFFIDdIEG`	`FIFskWTLREGWDnPNVFVIA`	`SESSKIQEVGRAvR`
LlaFI Res	`LLFNMATGSGKTMVMAS`	`QNFIFLVnTdAIIKKT`	`VILGDEAH`	`LLEFSATIN`	`TVEsLVkYLK`	`VIFAvAKLNEGWDVLNLYDIV`	`ATDSEAQLVGRGAR`
Consensus	`+++ tg GKT +`	`+++++p r +`	`++++DEah`	`++++sat`	`+++f t`	`++++t + g + + + ++`	`q +GR+ar`

Boldface type indicates amino acids which are either completely conserved or replaced by similar amino acids. Plus signs represent hydrophobic amino acid residues. The consensus residues determined by Gorbalenya et al. (15) are indicated.