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. 2022 May 2;13:843815. doi: 10.3389/fneur.2022.843815

Figure 4.

Figure 4

Significant alternations in ALFF induced by CCI and correlations between ALFF values and the mechanical withdrawal thresholds (MWT) values, open field test (OFT) data, and forced swimming test (FST) data. (A) CCI group rats were found to exhibit significantly lower ALFF values in the left somatosensory cortex on day 11 after CCI surgery and significantly higher ALFF values in both the left somatosensory cortex and mPFC on day 32 after CCI surgery as compared to sham group rats; (B) ALFF values in the left somatosensory cortex (10 days after CCI surgery) positively correlated with MWT values (7 days after CCI surgery); (C–H) ALFF values in the left somatosensory cortex and mPFC (32 days after CCI surgery) negatively correlated with MWT (28 days after CCI surgery), distance traveled and time spent in the central zone of OFT (29 days after CCI surgery); (I,J) The ALFF values in the left somatosensory cortex and mPFC (32 days after CCI surgery) was positively correlated with immobility time on FST (31 days after CCI surgery).