TABLE 1.
Subject | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | Mean |
Age | 77 | 76 | 66 | 63 | 65 | 74 | 82 | 63 | 70.8 |
Gender | F | F | M | F | F | F | M | F | – |
ApoE Genotype | 2/3 | 3/3 | 3/3 | 3/3 | 2/3 | 3/3 | 2/3 | 3/3 | – |
GDS Rating | 4 | 4 | 3 | 5 | 4 | 3 | 4 | 4 | 3.9 |
Education (years) | 19 | 16 | 15 | 13 | 14 | 16 | 12 | 14 | 14.9 |
Anat. MRI Analysis | b,c | b,c | b | c | b | a,b | b,c | a | – |
PET AD Sign. ROI | 1.10 | 1.06 | 1.10 | 1.32 | 1.40 | 1.25 | 1.06 | 1.32 | 1.20 |
Aβ1-42/t-tau Ratio | 1.48 | 1.02 | 0.93 | 0.61 | – | 0.99 | 0.98 | 0.30 | 0.90 |
ADAS-cog13 Score | 24 | 26.7 | 30.3 | 30.7 | 37.3 | 38.7 | 44.0 | 62.0 | 36.7 |
a, frontal/parietal lobe atrophy; b, hippocampal/temporal lobe atrophy; c, global cortical atrophy.