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. 2022 May 2;16:819310. doi: 10.3389/fnins.2022.819310

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Copyright © 2022 Dong, Yin, Yu, He, Chen, Ma, Qu, Yin, Liu, Zhang, Huang, Lu, Gong and Zeng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cerebral activity changes induced by the acupuncture stimulation in two groups. (A) A significantly increased ALFF was found in the left postcentral gyrus after acupuncture treatment. (B) Correlation analysis showed that the change of ALFF value in left postcentral gyrus and the improvement of SID were positively correlated with age and gender as covariates (r = 0.358, p = 0.041). (C) After acupuncture treatment, the decreased rsFC between the left postcentral gyrus with angular, caudate, MFG, and cerebellum were found in group A. (D) After acupuncture treatment, the increased rsFC between the left postcentral gyrus with precuneus, SFG, and MFG was found in group B. ALFF, amplitude of low-frequency fluctuation; rsFC, resting-state functional connectivity; MFG, middle frontal gyrus; SID, Symptom Index of Dyspepsia; SFG, superior frontal gyrus.