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. 2022 May 2;13:872188. doi: 10.3389/fphar.2022.872188

FIGURE 1.

FIGURE 1

Naringenin promotes osteogenic differentiation of BMSCs. (A,C) ARS staining and its quantification. (B,D) ALP staining and its quantification. (E) Transcript levels of osteoblast markers Runt-related transcription factor 2 (Runx2), alkaline phosphatase (Alp), and bone gamma-carboxyglutamate protein (Bglap). (F,G) Western blot and optical density analysis of RUNX2 and OCN with Gapdh as reference. n = 4 per group. Data are expressed as mean ± SD. ∗ p < 0.05; ∗∗ p < 0.01; ∗∗∗ p < 0.001. ∗ compared with con group.