Table 1.
Influence of NAC in VCM-induced changes of metabolic parameters.
| Control | NAC (10 mg/kg) |
NAC (30 mg/kg) |
Vit C (200 mg/kg) |
|
|---|---|---|---|---|
| Initial weight (g) | 202.68±4.74 | 204.90±3.15 | 206.82±4.07 | 201.94±3.73 |
| Final weight (g) | 258.64±9.83 | 235.83±7.95 | 231.71±14.90 | 249.89±8.16 |
| Kidney weight (g) | 1.01±0.05 | 0.89±0.04 | 0.96±0.06 | 0.90±0.03 |
| Kidney index (%) | 0.40±0.02 | 0.36±0.03 | 0.41±0.02 | 0.47±0.05 |
| Food intake (g) | 20.72±0.96 | 19.29±1.91 | 19.97±4.80 | 18.31±2.25 |
| VCM | VCM+NAC (10 mg/kg) |
VCM+NAC (30 mg/kg) |
VCM+Vit C (200 mg/kg) |
|
| Initial weight (g) | 210.33±5.50 | 209.16±8.43 | 206.28±1.73 | 204.65±4.65 |
| Final weight (g) | 179.27±7.98** | 230.53±10.70# | 206.92±11.29# | 204.17±9.05# |
| Kidney weight (g) | 2.48±0.96** | 1.16±0.08# | 1.28±0.13# | 1.19±0.09# |
| Kidney index (%) | 1.36±0.41** | 0.50±0.04# | 0.59±0.07# | 0.58±0.03# |
| Food intake (g) | 5.18±1.32** | 14.28±1.32# | 10.88±1.80# | 10.79±2.08# |
Table 1. Data was performed from 5 rats and presented as mean ± SEM. **p<0.01, significantly different with that in the control group. #p<0.05, significantly different with that in the VCM group. The significance was analyzed by ANOVA followed by Tukey's test.