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. 2022 May 2;9:871682. doi: 10.3389/fnut.2022.871682

Table 2.

Physical and biochemical parameters of IF vs. CR.

No. of studies SMD/WMD 95%CI p I2 (%) Effect-model
Weight 6 2.08 −0.61–4.77 0.13 22 Fixed
BMI 11 0.35 −0.64–1.34 0.49 57 Random
WC 10 2.29 0.57–4.01 0.009 35 Fixed
FM(kg) 12 1.96 −0.34–4.27 0.09 72 Random
FM% 8 0.77 −0.62–2.16 0.28 5 Fixed
FFM(kg) 10 0.65 −0.51–1.81 0.27 0 Fixed
SBP 9 1.75 −0.41–3.90 0.11 45 Fixed
DBP 9 1.06 −0.53–2.65 0.19 0 Fixed
Glucose 12 −0.01 −0.16–0.14 0.87 22 Fixed
Insulin 10 0.07 −0.09–0.22 0.40 44 Fixed
HOMA-IR 7 0.00 −0.31–0.32 0.99 54 Random
TG 10 0.03 −0.14–0.19 0.76 20 Fixed
TC 10 0.08 −0.09–0.24 0.35 0 Fixed
LDL 9 0.06 −0.11–0.23 0.49 0 Fixed

CR, calorie restriction; IF, intermittent fasting; BMI: body mass index; WC, waist circumference; FM, fat mass; FFM, fat-free mass; SBP, systolic blood pressure; DBP, diastolic blood pressure; HOMA-IR, homeostasis model assessment insulin resistance; TC, total cholesterol; TG, triglyceride; LDL, low-density lipoprotein; SMD, standard mean difference; WMD, weighted mean difference; CI, confidence interval. SMD: glucose, insulin, TG, TC, and LDL; WMD: weight, BMI, WC, FM (kg), FM%, FFM (kg), SBP, DBP, and HOMA-IR.

Bold indicates statistically significant differences (P < 0.05).