Table 6.
Physical and biochemical parameters of IF vs. CR in patients with BMI ≥25 kg/m2.
| No. of studies | SMD/WMD | 95%CI | p | I2 (%) | Effect-model | |
|---|---|---|---|---|---|---|
| Weight | 13 | 0.25 | −2.88–3.37 | 0.88 | 52 | Random |
| BMI | 11 | 0.35 | −0.64–1.34 | 0.49 | 57 | Random |
| WC | 7 | 1.58 | −0.60–3.76 | 0.16 | 36 | Fixed |
| FM(kg) | 9 | 1.61 | −1.32–4.54 | 0.28 | 74 | Random |
| FM% | 6 | 0.54 | −1.13–2.21 | 0.53 | 26 | Fixed |
| FFM(kg) | 8 | −0.13 | −1.70–1.44 | 0.87 | 0 | Fixed |
| SBP | 9 | 1.75 | −0.41–3.90 | 0.11 | 45 | Fixed |
| DBP | 9 | 1.06 | −0.53–2.65 | 0.19 | 0 | Fixed |
| Glucose | 10 | 0.05 | −0.12–0.23 | 0.55 | 16 | Fixed |
| Insulin | 9 | 0.02 | −0.15–0.19 | 0.82 | 42 | Fixed |
| HOMA-IR | 6 | −0.18 | −0.39–0.03 | 0.10 | 46 | Fixed |
| TG | 10 | 0.03 | −0.14–0.19 | 0.76 | 20 | Fixed |
| TC | 9 | 0.08 | −0.09–0.25 | 0.35 | 0 | Fixed |
| LDL | 9 | 0.06 | −0.11–0.23 | 0.49 | 0 | Fixed |
| HDL | 9 | 0.02 | −0.15–0.19 | 0.79 | 42 | Fixed |
CR, calorie restriction; IF, intermittent fasting; BMI: body mass index; WC, waist circumference; FM, fat mass; FFM, fat-free mass; SBP, systolic blood pressure; DBP, diastolic blood pressure; HOMA-IR, homeostasis model assessment insulin resistance; TC, total cholesterol; TG, triglyceride; LDL, low-density lipoprotein; HDL, high-density lipoprotein; SMD, standard mean difference; WMD, weighted mean difference; CI, confidence interval. SMD: glucose, insulin, TG, TC, LDL, and HDL; WMD: weight, BMI, WC, FM (kg), FM%, FFM (kg), SBP, DBP, and HOMA-IR.