TABLE 1.
Characteristics of the 635 HNSCC patients.
| Characteristic | Clinical feature | Total | GSE65858 | TCGA-HNSCC | p-value |
|---|---|---|---|---|---|
| Gender | Female | 151(23.78%) | 38(16.96%) | 113(27.49%) | 0.004 |
| Male | 484(76.22%) | 186(83.04%) | 298(72.51%) | ||
| Age | ≤65 | 408(64.25%) | 148(66.07%) | 260(63.26%) | 0.536 |
| >65 | 227(35.75%) | 76(33.93%) | 151(36.74%) | ||
| Stage a | Stage I–II | 128(20.16%) | 45(20.09%) | 83(20.19%) | 0.399 |
| Stage III–IV | 450(70.87%) | 179(79.91%) | 271(65.94%) | ||
| Unknown | 57(8.98%) | 0(0%) | 57(13.87%) | ||
| T stage a | T1-2 | 255(40.16%) | 98(43.75%) | 157(38.2%) | 0.951 |
| T3-4 | 333(52.44%) | 126(56.25%) | 207(50.36%) | ||
| Unknown | 47(7.4%) | 0(0%) | 47(11.44%) | ||
| N stage a | N0 | 203(31.97%) | 72(32.14%) | 131(31.87%) | 0.080 |
| N1-3 | 350(55.12%) | 152(67.86%) | 198(48.18%) | ||
| Unknown | 82(12.91%) | 0(0%) | 82(19.95%) | ||
| M stage a | M0 | 368(57.95%) | 218(97.32%) | 150(36.5%) | 0.109 |
| M1 | 6(0.94%) | 6(2.68%) | 0(0%) | ||
| Unknown | 261(41.1%) | 0(0%) | 261(63.5%) |
a
Staging according to the seventh edition AJCC guidelines.
The clinical characteristic differences between TCGA and GSE65858 datasets based on the χ2 test and with continuity correction where appropriate.