Figure 2.

Evaluation of cognitive, memory impairments, and Aβ–Tau pathological hallmarks of AD model mice. A) The representative swimming paths of mice in the MWM test. B) Latency (n = 8). C) Percent time spent on the targeted quadrant (n = 8). D) Times across the platform (n = 8). E) Western blot results of p‐Akt, Akt, p‐GSK3β, GSK3β, p‐Tau, and Tau in mice brain. F) Immunostaining of Aβ in the whole brain and representative of DG region of the hippocampus. Scale bars = 2 mm or 100 µm. Data were presented as mean ± SD. *p < 0.05, **p < 0.01, and ***p < 0.001.