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. 2022 Apr 19;86(4):1917–1933. doi: 10.3233/JAD-215059

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© 2022 – The authors. Published by IOS Press

This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 5 — Signaling pathways towards AβPP phosphorylation. Graphical view of signaling pathways of the top 6 proteins with higher betweenness centrality values from Fig. 4 towards AβPP using the kinector tool. 1) LRRK2 signaling pathway towards AβPP. 2) GSK3B signaling pathway towards AβPP. 3) AKT1 signaling pathway towards AβPP. 4) EGFR signaling pathway towards AβPP. 5) ERK2 signaling pathway towards APP. 6) FYN signaling pathway towards AβPP.