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. 2022 Apr 22;25(5):104279. doi: 10.1016/j.isci.2022.104279

Figure 1.

Figure 1

The miR-25 level is induced by Bacillus Calmette–Guérin and Mtb infection

(A and B) Quantitative real-time PCR (qRT-PCR) detection of the expression of miRNAs in the lungs of the control group or mice (n = 3) infected with 4.4 × 105 CFU BCG via tail vein for 3 days (A) and 7 days (B).

(C) qRT-PCR detection of the expression of miRNAs in THP-1 cells of the control group or cells infected with BCG or H37Rv.

(D) qRT-PCR detection of the expression of miR-25 in THP-1 cells infected with BCG at the indicated MOIs for 24 h.

(E) qRT-PCR detection of the expression of miR-25 in THP-1 cells infected with BCG for 6, 12 and 24 h.

(F) qRT-PCR detection of the expression of miR-25 in THP-1 cells infected with H37Rv at the indicated MOIs for 24 h.

(G) qRT-PCR detection of the expression of miR-25 in THP-1 cells infected with H37Rv for 6, 12 and 24 h. Data are presented as means ± SD. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.005, ns, not significant.