Table 1.

Correlation between ACYP1 expression and immune cell markers in LIHC.

Cell type	Gene markers	Cor	p
B cell	CD19	0.238	0.000008	***
	CD79A	0.167	0.001880	**
T cell	CD3D	0.303	0.000000	***
	CD3E	0.24	0.000007	***
	CD2	0.223	0.000029	***
CD8+ T cell	CD8A	0.205	0.000128	***
	CD8B	0.208	0.000099	***
Th1	T-bet	0.096	0.074700
	IL-2	0.116	0.031700	*
	IFN-γ	0.243	0.000005	***
	TNF	0.272	0.000000	***
Th2	GATA3	0.261	0.000001	***
	STAT5A	0.242	0.000005	***
	IL13	0.178	0.000896	***
Th17	STAT3	0.147	0.006170	**
	IL17A	0.08	0.137000
Tfh	BCL6	0.212	0.000075	***
	IL21	0.071	0.189000
Treg	FOXP3	0.214	0.000061	***
	CCR8	0.312	0.000000	***
	STAT5B	0.187	0.000495	***
	TGFβ	0.325	0.000000	***
T cell exhaustion	PD-1	0.237	0.000009	***
	CTLA-4	0.359	0.000000	***
	LAG3	0.274	0.000000	***
	TIM-3	0.379	0.000000	***
	GZMB	0.152	0.004630	**
	TOX	0.228	0.000019	***
	TIGIT	0.305	0.000000	***
TAM	CCL2	0.232	0.000013	***
	CD68	0.205	0.000122	***
	IL10	0.239	0.000007	***
M1 macrophage	iNOS	0.087	0.109000	n.s.
	IRF5	0.366	0.000000	***
	COX2	0.276	0.000000	***
M2 macrophage	CD163	0.109	0.042400	*
	VSIG4	0.185	0.000547	***
	MS4A4A	0.172	0.001380	**
Neutrophils	CD66b	0.094	0.081200	n.s.
	CD11b	0.337	0.000000	***
NK	CD16	0.330	0.000000	***
	CD56	0.346	0.000000	***
DC	CD1c	0.103	0.057100	n.s.
	CD83	0.37	0.000000	***
	CD209	0.104	0.053600	n.s.
	MHCII	0.219	0.000042	***
Monocyte	CD14	-0.301	0.000000	***
	CD64	0.338	0.000000	***
	CD15	0.368	0.000000	***

LIHC, liver hepatocellular carcinoma; Tfh, follicular helper T cell; Th, T helper cell; Treg, regulatory T cell; TAM, tumor associated macrophage; NK, natural killer cell; DC, dendritic cell; Cor, R value of Spearman’s correlation. ^*P < 0.05, ^**P < 0.01, ^***P < 0.001.

n.s. "no significance".