Figure 1.

TSA improved liver injury and inflammation and promoted autophagy and the expression of FoxO3a in the septic mice. A: the liver injury evaluated by H&E staining (200×); B: electron microscope results of the liver tissue in each group after different treatments (12,000×); C: the expression of LC3, P62, and FoxO3a in the liver tissue measured by Western blotting; D: immunofluorescence results of LC3 in the liver tissue after different treatments (400×). TSA: trichostatin A; CLP: cecal ligation and puncture; H&E: hematoxylin-eosin; DAPI: 4’,6-diamidino-2-phenylindole.