Fig. 3.

Hippocampal injury inversely correlates with flurothyl seizure susceptibility after neonatal hypoxia-ischemia in a sex-specific manner. A Hippocampal injury and GFAP scores are directly correlated in the whole group of pups, and stratified by sex (A₁, A₂). B, B₁, B₂ Composite hippocampal injury does not correlate with latency (in seconds) to stage 3 seizure. C Composite hippocampal injury correlates with latency (in seconds) to stage 5 seizure. When stratified by sex, this correlation is seen in male pups only (C₁ vs. C₂). Nonparametric Spearman Rho correlation statistics were used.