Table 1.
Summary of reports about CDS in immunocompetent patients.
| Report | Patient’s Characteristics | Risk Factors and/or Inoculation entry | Clinical Manifestations | Onset of the disease | Diagnostic Method | Molecular identification | Treatment |
|---|---|---|---|---|---|---|---|
| Seow et al., 2022 [10] | Male, 50 years old, Malasian | Gardening and contact with feces from cats | Multiple nodules and fever | 1 month | Direct exam/Histopathology + culture | Not performed | Amphotericin B deoxycholate 0.7 mg/kg/day/Itraconazole 200mg twice daily |
| Garcia et al., 2021 [11] | Female, 37 years old, USA | Gardening | Multiple nodules and arthralgias | 2 months | Culture | Not performed | Itraconazole 200mg twice daily |
| Martínez-Herrera et al., 2021 [12] | Male, 21 years old, Mexican | None | Multiple ulcerated nodules | 2 years | Culture | Sporothrix schenkii | Potassium iodide 3.5 g day |
| Valeriano et al., 2020 [19] | Female, 26 years old, Brazilian Female, 46 years old, Brazilian |
Cat bites Cat scratches |
Multiple nodules Multiple ulcerated nodules |
40 days 2 months |
Direct exam/Histopathology + culture Direct exam/Histopathology + culture |
Sporothrix brasiliensis Sporothrix brasiliensis |
Itraconazole 200mg day Itraconazole 100mg day |
| Medeiros et al., 2016 [14] | Female, 59-year-old, Brazilian | Contact with cats | Multiple nodules, conjunctivitis | 2.5 months | Culture | Not performed | Itraconazole 200mg day |
| Yap, 2011 [15] | Female, 70 years old, Malasian | Gardener and 2 pets | Papular lesions on lower limbs | 6 months | Direct exam/Histopathology + culture | Nor performed | Itraconazole 400mg day |
| Romero-Cabello et al., 2011 [16] | Male, 36 years old, Mexican | Long term farmer | Multiple ulcerated nodules on skin of dorsum and anterior abdomen | 3 years | Culture | Sporothrix schenkii | Itraconazole + Potassium iodide + Amphotericin B 0.5 mg/kg/day |
| Cullen et al., 1992 [17] | Male ,71 years old, USA | None | Multiple ulcerated nodules and fever | 3 months | Culture | Not performed | Ketoconazole 200mg day |
| Boehm et al., 1982 [18] | Male, 50 years old, USA | None | Multiple ulcerated nodules on skin of forearm and lung involvement | 5 months | Direct exam/Histopathology + culture | Not performed | Amphotericin B |