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. 2022 Apr 25;65(9):6513–6540. doi: 10.1021/acs.jmedchem.1c01756

Table 5. In Vivo Pharmacokinetic Parameters for 34ba.

cmpd Cl (mL/min/kg) Vd (L/kg) t1/2 (min) F (%)
34b 14 0.6 80 42
a

In vivo studies were performed at a dose of 10 mg/kg i.v. and 10 mg/kg p.o. in mouse.