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. Author manuscript; available in PMC: 2022 May 16.
Published in final edited form as: Nano Lett. 2020 Aug 31;20(10):7159–7167. doi: 10.1021/acs.nanolett.0c02487

Figure 4.

Figure 4.

In vivo tumor targeting of Au–Gd(III)-PSMA NPs and MR imaging. T1-weighted spin echo images of mice with PC3pip tumor (a) and PC3flu tumor (b) obtained at 7 T. Tumors are indicated by red triangles and bladders are indicated by green arrows. Representative images are shown of n = 3. (c) Contrast-to-noise ratio (CNR) of PC3pip and PC3flu tumors relative to muscle, computed from T1-weighted images (n = 3). (d) Au and Gd(III) content in PC3pip and PC3flu tumors 24 h after Au–Gd(III)-PSMA NPs injection. Data are presented as the mean ± SD (n = 3), and differences between groups are compared with two-tailed t tests, **p ≤ 0.01.