Table 1.

Epigenetic modifying enzymes shared both in the circadian clock and in the MSC fate decisions

Circadian component	Epigenetic regulators	Differentiation signals	References
BMAL1-CLOCK	P300/CBP; miR-7-5p	RUNX2	[66]
REV-ERBα/RORα	HDACs	NF-κB	[104]
SIRT1	SIRT1	PPARγ; RUNX2; SOX9; Wnt/β-catenin	[105]
Bmal1	EZH2	BMP2; ATOH8	[106, 107]
Bmal1	DNMT3	Collagen type II	[108]