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. 2022 May 16;23:186. doi: 10.1186/s12882-022-02816-5

Table 2.

Comparisons of physical function with muscle quality (EI) and muscle quantity (CSA) in patients on hemodialysis

Model 1 Model 2 Model 3
β (SE) P-value β (SE) P-value β (SE) P-value
HGS (kg)
  EI  − 0.207 (0.047)  < 0.001  − 0.171 (0.046)  < 0.001  − 0.090 (0.047) 0.061
  CSA 2.527 (0.479)  < 0.001 1.912 (0.500)  < 0.001 1.393 (0.483) 0.005
Gait speed (m/s)
  EI  − 0.002 (0.001) 0.028  − 0.002 (0.001) 0.017  − 0.002 (0.001) 0.130
  CSA 0.030 (0.010) 0.003 0.035 (0.011) 0.002 0.030 (0.011) 0.009
STS-60 (repetitions)
  EI  − 0.136 (0.049) 0.006  − 0.150 (0.050) 0.003  − 0.081 (0.051) 0.119
  CSA 0.892 (0.497) 0.075 1.131 (0.539) 0.038 0.747 (0.522) 0.156
Odds ratio (95% CI) P-value Odds ratio (95% CI) P-value Odds ratio (95% CI) P-value
Dependency in IADL
  EI 1.070 (1.030–1.1112) 0.001 1.100 (1.049–1.155)  < 0.001 1.086 (1.033–1.141) 0.001
  CSA 0.569 (0.376–0.860) 0.008 0.369 (0.216–0.633)  < 0.001 0.438 (0.255–0.755) 0.003

Multiple linear regression for continuous outcomes and logistic regression for dichotomous outcomes. Model 1: EI + CSA; Model 2: EI + CSA + sex; Model 3: EI + CSA + sex + age + dialysis duration

HGS Handgrip strength, EI Echo intensity, CSA Cross-sectional area, STS-60 Sit-to-stand 60 s, IADL Instrumental activities of daily living