. 2022 May 16;2:20. doi: 10.1186/s44158-022-00048-5

Table 3.

SF-36 domain scores according to demographics, socio-economic, and clinical characteristics in C-ARDS survivors

			*Physical function*	*Physical role*	*Bodily pain*	*General health*	*Vitality*	*Social function*	*Emotional role*	*Mental health*
Age (years)	< 65	43	90	75	90	40	65	75	100	80
	< 65	43	(80–98)	(0–100)	(68–100)	(25–60)	(53–70)	(50–88)	(67–100)	(70–88)
	> 65	36	85	13	76	48	55	63	100	78
	> 65	36	(64–95)	(0–100)	(45–100)	(20–70)	(40–71)	(25–100)	(67–100)	(56–88)
	p		p = 0.2158	p = 0.5171	p = 0.1615	p = 0.6715	p = 0.3882	p = 0.4159	p = 0.9152	p = 0.5626
Education (ISCED)	0–2	28	85	50	90	50	60	88	100	84
	0–2	28	(80–98)	(0–100)	(68–100)	(20–70)	(45–78)	(50–100)	(100–100)	(64–92)
	> 2	51	85	25	78	45	55	63	100	76
	> 2	51	(63–95)	(0–100)	(45–100)	(25–60)	(45–70)	(25–88)	(33–100)	(64–88)
	p		p = 0.3815	p = 0.9121	p = 0.0920	0.4841	p = 0.5873	p = 0.1362	p = 0.1990	p = 0.2109
Monthly income (€)	< 1500	41	85	0	88	45	55	63	100	80
	< 1500	41	(80–95)	(0–100)	(50–100)	(25–60)	(45–70)	(25–88)	(67–100)	(68–88)
	> 1500	35	90	100	78	50	65	75	100	80
	> 1500	35	(70–98)	(0–100)	(55–100)	(20–75)	(50–70)	(56–100)	(83–100)	(64–88)
	p		p = 0.7281	p = 0.1537	p = 0.8466	p = 0.2239	p = 0.3575	p = 0.1844	p = 0.7816	p = 1.000
Comorbidities	0–1	61	90	50	90	50	65	88	100	80
	0–1	61	(80–100)	(0–100)	(68–100)	(30–70)	(50–75)	(50–100)	(100–100)	(68–88)
	> 1	18	70	0	50	15	45	31	0	62
	> 1	18	(4–90)	(0–100)	(25–85)	(5–45)	(26–55)	(13–75)	(0–100)	(45–80)
	p		p = 0.0037^a	p = 0.2446	p = 0.0018^a	p = 0.004^a	p = 0.0010^a	p = 0.0021^a	p < 0.0001^a	p = 0.0017^a
PaO₂/FiO₂ on ICU admission	< 150	34	83	0	78	33	55	56	100	80
	< 150	34	(65–95)	(0–100)	(38–100)	(16–58)	(41–69)	(25–88)	(0–100)	(58–88)
	> 150	44	90	100	90	48	60	88	100	76
	> 150	44	(80–96)	(0–100)	(55–100)	(29–71)	(50–71)	(50–100)	(0–100)	(64–88)
	p		p = 0.1007	p = 0.0388^a	p = 0.0529	p = 0.0313^a	p = 0.1276	p = 0.0225^a	p = 0.0330^a	p = 0.4059
SAPS II	< 25	28	90	75	90	38	63	75	100	78
	< 25	28	(85–100)	(0–100)	(68–100)	(16–54)	(55–74)	(50–88	(67–100)	(62–88)
	> 25	51	85	25	76	50	55	75	100	80
	> 25	51	(65–95)	(0–100)	(45–100)	(25–70)	(45–70)	(25–100	(67–100)	(64–88)
	p		p = 0.0202^a	p = 0.2835	p = 0.0363^a	0.9283	p = 0.1268	p = 0.1481	p = 0.4662	p = 0.5614
Ventilation (days)	≤ 15	36	90	100	90	45	63	88	100	82
	≤ 15	36	(80–100)	(0–100)	(64–100)	(25–71)	(54–80)	(50–100)	(100–100)	(71–88)
	> 15	43	85	0	78	45	55	63	100	72
	> 15	43	(63–95)	(0–100)	(48–100)	(20–61)	(38–70)	(31–88)	(33–100)	(58–88)
	p		p = 0.0388^a	p = 0.0043^a	p = 0.0396^a	p = 0.2556	p = 0.0500	p = 0.0187^a	p = 0.0672	p = 0.0650
Hospital LOS (weeks)	≤ 4	23	90	100	100	45	60	88	100	84
	≤ 4	23	(85–100)	(0–100)	(89–100)	(20–63)	(55–80)	(50–100)	(100–100)	(70–88)
	> 4	56	85	0	73	45	58	75	100	76
	> 4	56	(64–95)	(0–100)	(45–100)	(20–65)	(40–70)	(25–88)	(33–100)	(59–88)
	p		p = 0.0344^a	p = 0.0112^a	p = 0.0025^a	p = 0.4634	p = 0.0411^a	p = 0.0945	p = 0.0806	p = 0.1061

SF-36 scores for each domain can range from 0 to 100; higher scores correspond to a better health-related quality of life. Data are espressed as median (25th–75th) percentile of SF-36 domains score and analyzed with Mann-Whitney U-test; ^acorresponds to significant differences between groups; p < 0.05 was considered significant. ISCED, International Standard Classification of Education. ISCED 0, early childhood education (“less than primary” for educational attainment)

ISCED 1 primary education, ISCED 2 lower secondary education, ISCED 3 upper secondary education, ISCED 4 postsecondary non-tertiary education, ISCED 5 short-cycle tertiary education, ISCED 6 bachelor’s or equivalent level, ISCED 7 master’s or equivalent level, ISCED 8 doctoral or equivalent level, ICU intensive care unit, SAPS II Simplified Acute Physiology Score, LOS length of stay; ventilation (days), duration of ventilation with PEEP ≥ 5 cmH₂0