Table 3.
Laboratory characteristics of DM patients with MDA5 antibody and MAS in the literature.
| Studies | Year | ALT (U/l) | AST (U/l) | LDH (U/l) | CK (U/l) | Ferritin (ng/ml) | Ro Abs | Blood cells |
|---|---|---|---|---|---|---|---|---|
| Wakiguchi et al. 6 | 2015 | 596 | 1154 | 2267 | 40 | 8062 | ND | WBC 2.56 × 109/l, HGB 13.4 g/dl, PLT 119 × 109/l |
| Yoshimatsu et al. 7 | 2015 | 94 | 108 | 451 | 1483 | 2929 | ND | WBC 5.6 × 109/l, HGB 13.0 g/dl, PLT 100 × 109/l |
| Fujita et al. 8 | 2018 | 1435 | 1439 | 710 | 746 | 5953 | ND | WBC 3.0 × 109/l, HGB 15.1 g/dl, PLT 74 × 109/l |
| Honda et al. 9 | 2019 | ND | ND | ND | 8430, 32, 277 | 59,877, 11,498, 4876 | + | Cytopenia |
| Kishida et al. 10 | 2020 | 38 | 72 | 499 | 1120 | 971 | – | WBC 1.55 × 109/l, HGB 10.2 g/dl, PLT 39 × 109/l |
| Paul et al. 11 | 2020 | ND | ND | 490 | 279 | 1600 | – | Thrombocytopenia and anemia |
Abs, antibodies; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CK, creatine kinase; DM, dermatomyositis; HGB, hemoglobin; LDH, lactate dehydrogenase; MAS, macrophage activation syndrome; MDA5, melanoma differentiation-associated gene 5; ND, not described; PLT, platelets; WBC, white blood cells.