Appendix Table 1.

Conditions That Increase the Risk for Influenza Complications^*

Conditions Associated With Elevated Riskfor Influenza Complications (High-Risk Conditions)†	Diagnosis of Chronic Conditions and Other Disabling Conditions‡
Blood disorders	Anemia Sickle cell disease
Immunosuppressed conditions	HIV/AIDS Leukemia and lymphoma
Cancer	Breast cancer Colorectal cancer Endometrial cancer Lung cancer Prostate cancer
Chronic lung disease	Asthma Chronic obstructive pulmonary disease Cystic fibrosis and other metabolic developmental disorders
Endocrine disorders	Acquired hypothyroidism Diabetes
Heart disease	Acute myocardial infarction Atrial fibrillation Heart failure Hyperlipidemia Hypertension Ischemic heart disease Peripheral vascular disease Stroke or transient ischemic attack
Kidney disorders	Chronic kidney disease
Liver disorders	Liver disease, cirrhosis, and other liver conditions (excluding hepatitis) Viral hepatitis (general)
Neurologic and neurodevelopmental conditions	Alzheimer disease Alzheimer disease and related disorders or senile dementia Cerebral palsy Epilepsy Intellectual disabilities and related conditions Learning disabilities Multiple sclerosis and transverse myelitis Muscular dystrophy Other developmental delays Spina bifida and other congenital anomalies of the nervous system Spinal cord injury Traumatic brain injury and nonpsychotic mental disorders due to brain damage
Persons with extreme obesity (body mass index ≥40 kg/m2)	Obesity

^*A person could be diagnosed with >1 high-risk disease or symptom within a single high-risk condition (e.g., a person diagnosed with hyperlipidemia, hypertension, and ischemic heart disease would be listed only under the heart disease condition).

^†From reference 1.

^‡From reference 11.