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. 2022 May 13;10:e13442. doi: 10.7717/peerj.13442

Figure 2. Exosome uptake by BMSCs and exosomes mediating the inflammatory response.

Figure 2

(A) Images of exosome uptake by BMSCs in fluorescence confocal microscopy. BMSCs nuclei were stained with Hoechst (blue), BMSCs Cytoskeleton were stained with FITC-Phalloidin (red), macrophage-derived exosomes were labelled with PKH67 (green). (B–D) The protein expression of TNF-α and IL-6. (E–F) The mRNA expression levels of TNF-α and IL-6. An asterisk (*) indicates P < 0.05, two asterisk (**) indicates P < 0.01, three asterisks (***) indicate P < 0.001, four asterisks (****) indicate P < 0.0001, ns indicate P > 0.05, ns indicates no significant difference.