Table 2.
Clinical characteristics of 19 patients with pneumonitis
| Pt | Tumor | sex | Age, year | Agents | ILD | LM | Smoking history | Smoking amount, pack-years | Time to the onset of pneumonitis, day | Grade | Radiographic pattern |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | HNC (Sq) | M | 73 | NIVO | − | + | F | 67.5 | 112 | 1 | OP + NSIP |
| 2 | HNC (Sq) | M | 79 | NIVO | + | − | F | 57 | 42 | 1 | OP + NSIP |
| 3 | HNC (Undifferentiated) | M | 68 | NIVO | + | + | F | 48 | 87 | 2 | NSIP |
| 4 | HNC (Sq) | po | 66 | NIVO | − | + | C | 22.5 | 59 | 1 | OP + NSIP |
| 5 | HNC (Sq) | M | 71 | NIVO | − | − | F | 40 | 6 | 1 | OP |
| 6 | HNC (Sq) | M | 69 | NIVO | − | + | C | 50 | 111 | 5 | NSIP |
| 7 | MM | F | 78 | NIVO | − | − | N | 0 | 105 | 1 | OP |
| 8 | GC (AdSq) | M | 72 | NIVO | − | + | C | 26.5 | 456 | 2 | NSIP |
| 9 | GC (Ad) | M | 58 | NIVO | − | + | C | 36 | 20 | 1 | OP |
| 10 | GC (Ad) | M | 81 | NIVO | − | + | F | 15 | 287 | 1 | HP |
| 11 | RCC (clear cell) | M | 74 | NIVO | − | + | F | 36.75 | 771 | 2 | NSIP |
| 12 | RCC (clear cell) | M | 54 | NIVO | − | + | C | 16 | 371 | 2 | OP |
| 13 | RCC (clear cell) | M | 63 | NIVO | − | − | F | 64.5 | 105 | 2 | OP |
| 14 | RCC (clear cell) | F | 64 | NIVO | − | + | N | 0 | 25 | 2 | OP |
| 15 | RCC (clear cell) | M | 73 | NIVO | + | + | F | 22.5 | 129 | 2 | OP |
| 16 | RCC (clear cell) | M | 53 | NIVO | − | + | N | 0 | 1068 | 2 | NSIP |
| 17 | UC | M | 69 | PEM | + | + | C | 12 | 2 | 5 | NSIP |
| 18 | UC | M | 64 | PEM | − | + | F | 102 | 343 | 3 | OP |
| 19 | UC | M | 69 | PEM | − | + | F | 190 | 229 | 2 | OP |
Ad Adenocarcinoma, C Current, F Female, F Former, GC Gastric cancer, HNC Head and neck cancer, HP hypersensitivity pneumonitis, ILD Interstitial lung disease, LM Lung metastasis, M male, MM Malignant melanoma, N Never, NIVO Nivolumab, NSIP Nonspecific interstitial pneumonia, OP Organizing pneumonia, PEM Pembrolizumab, RCC Renal cell carcinoma, Sq Squamous carcinoma, UC Urothelial carcinoma