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. Author manuscript; available in PMC: 2022 May 16.
Published in final edited form as: Ann Intern Med. 2021 Jan 26;174(5):595–601. doi: 10.7326/M20-0469

Table 3:

Impact of the selected threshold for defining whether a woman complied with assigned protocol in a given week on the overall adherence adjusted effect estimates among 1,227 women in the EAGeR Trial, 2006-2012.

Risk Ratio (95% CI)
Compliant
Threshold
(compliant days
per week)
Proportion
Compliant
Observed
Live Birth Pregnancy Loss hCG Pregnancy
2 0.74 1.12 (0.91, 1.39) 0.89 (0.64, 1.24) 1.06 (0.97, 1.16)
3 0.72 1.10 (0.89, 1.36) 0.84 (0.62, 1.14) 1.04 (0.93, 1.17)
4 0.70 1.28 (1.06, 1.55) 0.71 (0.52, 0.97) 1.09 (1.00, 1.19)
5 0.67 1.33 (1.08, 1.64) 0.69 (0.50, 0.95) 1.12 (1.02, 1.23)
6 0.63 1.30 (1.09, 1.55) 0.71 (0.52, 0.97) 1.10 (1.00, 1.20)

Abbreviations: hCG, human chorionic gonadotropin.