Table 2. Comparison of outcome parameters in 110 hyperthyroid cats after radioiodine treatment, according to the radioiodine dosing method .
| Total | F group | I group | p | |
|---|---|---|---|---|
| Radioiodine therapy | ||||
| Dose (mean MBq) | 141 | 168 | 120 | <0.0001 |
| First recheck (1-3 months) | ||||
| Time to recheck (mean months) | 1.7 | 1.9 | 1.7 | 0.1 |
| T4 (median umol/L) | 19 | 21 | 18 | 0.41 |
| Creatinine (median umol/L) | 138 | 125 | 139 | 0.70 |
| Azotaemia | 8/54 (15%) | 4/22 (18%) | 4/32 (13%) | 0.56 |
| Second recheck (4-12 months) | ||||
| Time to recheck (mean months) | 6 | 5.6 | 6.8 | 0.04 |
| T4 (median nmol/L) | 21 | 22 | 20 | 0.53 |
| Creatinine (median umol/L) | 150 | 150 | 149 | 0.63 |
| Azotemia | 10/50 (20%) | 5/13 (39%) | 5/37 (13.5%) | 0.055 |
| Third recheck (> 12 months) | ||||
| Time to recheck (mean months) | 20.5 | 28 | 17.5 | 0.003 |
| T4 (median nmol/l) | 22 | 27 | 18 | 0.18 |
| Creatinine (median µmol/l) | 140 | 138 | 158 | 0.90 |
| Azotemia | 16/35 (46%) | 7/19 (37%) | 5/16 (31%) | 0.73 |
| Definitive thyroid status | ||||
| Median time to definitive status (months) | 11 | 14 | 10.5 | 0.11 |
| Euthyroidisma | 37/61 (61%) | 18/26 (69%) | 19/35 (54%) | 0.24 |
| Median survival time (months) | 44 | 47 | >29 | 0.25 |
a
Percentage of euthyroid cats represented after exclusion of cats with unclear thyroid status; (F group): group of cats receiving a fixed dose of radioiodine; (I group): group of cats receiving an individualized dose of radioiodine based on a clinical score P-value: less than 0.05.