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. 2022 May 16;17(5):e0268159. doi: 10.1371/journal.pone.0268159

Fig 8. Module 128 –stress and apoptosis related.

Fig 8

Panel A: thick red border: gene/protein annotated to be ALS-associated on any of the 7 lists. Large red label: gene/protein with GWAS evidence. Triangular shaped nodes: receptors (UniProt keyword). Node colors indicate subcellular location (UniProt keywords): Blue = Nuclear, Green = Secreted, Purple = conflicting nuclear/secreted, cyan = neither nuclear nor secreted (likely cytosolic). Panel B: Gene Ontology overrepresentation analysis. Panel C: Thick border: ALS-associated (as panel A), Colored node: Disease-associated gene/protein.