Figure 1.

The effects of EMPA on glucose tolerance and insulin resistance of db/db mice. (a and b) The oral glucose tolerance (OGTT) and (c and d) intraperitoneal insulin tolerance test (IPITT) were performed in WT mice treated with vehicle and db/db mice treated with EMPA or vehicle for 20 weeks. Area under the curve (AUC) for each test is shown in b and d. n = 5 per group. Data are shown as the mean ± SD, ^∗P < 0.05 vs. WT mice group; ^#P < 0.05 vs. db/db mice treated vehicle group.