Table 1.
Characteristics of patients by stability of diagnosis.
| Characteristics of patients by stability of diagnosis | Total (n = 1393) | No Dx change (n = 1308) | Dx change (n = 85) |
|---|---|---|---|
| Age at the first visit (years), mean (sd) | 70.3 (10.3) | 70.3 (10.3) | 70.4 (10.5) |
| Gender, n (column percent) | |||
| Male | 884 (63.9) | 824 (63.4) | 60 (70.6) |
| Female | 500 (36.1) | 475 (36.6) | 25 (29.4) |
| Race, n (column percent) | |||
| White | 1125 (90.7) | 1055 (90.5) | 70 (93.9) |
| Nonwhite | 116 (9.3) | 111 (9.5) | 5 (6.7) |
| Marital status, n (column percent) | |||
| Married | 986 (71.2) | 924 (71.0) | 62 (73.8) |
| Not married | 399 (28.8) | 377 (29.0) | 22 (26.2) |
| Education, n (column percent) | |||
| College or more | 918 (73.6) | 866 (73.7) | 52 (72.2) |
| Less than college | 329 (26.4) | 309 (26.3) | 20 (27.8) |
| Income, n (column percent) | |||
| <50 K/year | 244 (25.3) | 226 (25.0) | 18 (29.0) |
| >50 K/year | 722 (74.7) | 678 (75.0) | 44 (71.0) |
| Employment status, n (column percent) | |||
| Not employed | 826 (59.6) | 771 (59.2) | 55 (65.5) |
| Employed | 561 (40.4) | 532 (40.8) | 29 (34.5) |
| PD duration at the first visit (years), m (sd) | 4.5 (5.2) | 4.6 (5.3) | 3.1 (5.0) |
| PD duration at follow-up (years), m (sd)∗ | 5.4 (3.8) | 5.4 (3.8) | 4.9 (3.7) |
| First CIRS-G total score, m (sd)∗∗∗ | 4.9 (3.7) | 4.8 (3.6) | 6.4 (4.0) |
| First UPDRS motor score, m (sd)∗∗ | 26.2 (12.6) | 26.0 (12.6) | 29.8 (12.4) |
| First UPDRS total score, m (sd)∗ | 38.7 (18.4) | 38.4 (18.4) | 43.6 (18.3) |
| Change of the treating neurologist, n (column percent) | |||
| No | 807 (84.6) | 757 (84.5) | 50 (86.2) |
| Yes | 147 (15.4) | 139 (15.5) | 8 (13.8) |
| Levodopa at the first visit, n (column percent) | |||
| No | 813 (58.4) | 760 (58.1) | 53 (62.4) |
| Yes | 580 (41.6) | 548 (41.9) | 32 (37.6) |
| Levodopa at the last visit, n (column percent) | |||
| No | 626 (44.9) | 588 (45.0) | 38 (44.7) |
| Yes | 767 (55.1) | 720 (55.0) | 47 (55.3) |
| Dopaminergic Rx at the first visit, n (column percent) | |||
| No | 658 (47.2) | 613 (46.9) | 45 (52.9) |
| Yes | 735 (52.8) | 695 (53.1) | 40 (47.1) |
| Dopaminergic Rx at the last visit, n (column percent) | |||
| No | 579 (41.6) | 546 (41.7) | 33 (38.8) |
| Yes | 814 (58.4) | 762 (58.3) | 52 (61.2) |
| Dyskinesia at the first visit∗∗∗ | |||
| No | 1064 (80.5) | 986 (79.5) | 78 (95.2) |
| Yes | 258 (19.5) | 254 (20.5) | 4 (4.9) |
| Fluctuator at the first visit∗∗ | |||
| No | 953 (71.8) | 882 (70.8) | 71 (81.6) |
| Yes | 374 (28.2) | 363 (29.2) | 11 (13.4) |
| MMSE at the first visit, mean (sd) | 28.5 (2.1) | 28.5 (2.0) | 28.1 (2.7) |
∗ p < 0.05, ∗∗p < 0.01, and ∗∗∗p < 0.001.