. 2022 May 16;12:204. doi: 10.1038/s41398-022-01969-z

Table 3.

Pearson correlation estimates and p-values for the association between pre- to post-treatment change in 8-oxodG (Δ8-oxodG) and 8-oxoGuo (Δ8-oxoGuo), respectively, vs. pre- to post-treatment change in the predictor variables depressive symptoms (ΔHAM-D_6, ΔHAM-D₁₇), body mass index (ΔBMI), area under the curve of salivary cortisol excretion (full-day profile) (ΔAUC_full), high-sensitivity c-reactive protein (ΔhsCRP), and post-treatment plasma escitalopram concentration.

	ΔHAM-D₆	ΔHAM-D₁₇	ΔBMI	ΔAUC_full	ΔhsCRP	p-escitalopram
Δ 8-oxodG	0.15 p = 0.21	0.15 p = 0.18	−0.14 p = 0.21	−0.30 p = 0.0497	−0.04 p = 0.74	0.006 p = 0.96
Δ 8-oxoGuo	0.15 p = 0.20	0.15 p = 0.21	−0.03 p = 0.77	−0.49 p = 0.0009	−0.16 P = 0.16	0.24 p = 0.051

ΔHAM-D₆

ΔHAM-D₁₇

ΔBMI

ΔAUC_full

ΔhsCRP

p-escitalopram

Δ 8-oxodG

0.15

p = 0.21

0.15

p = 0.18

−0.14

p = 0.21

−0.30

p = 0.0497

−0.04

p = 0.74

0.006

p = 0.96

Δ 8-oxoGuo

0.15

p = 0.20

0.15

p = 0.21

−0.03

p = 0.77

−0.49

p = 0.0009

−0.16

P = 0.16

0.24

p = 0.051

Significant associations are in bold.